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Medications

Rolapitant injection

What is this medicine?

ROLAPITANT (roe LA pi tant) is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy).

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • dizziness

  • signs of decreased red blood cells - unusually weak or tired, feeling faint or lightheaded, falls

  • signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine

  • stomach pain

  • tingling or numbness

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • hiccups

  • loss of appetite

  • mouth sores

  • weight loss

What may interact with this medicine?

Do not take this medicine with any of these medicines:

  • pimozide

  • thioridazine

This medicine may also interact with the following medications:

  • certain medicines for blood pressure, heart disease, irregular heart beat

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, fosphenytoin

  • certain medicines that treat or prevent blood clots like warfarin and dabigatran

  • cyclosporine

  • dextromethorphan

  • digoxin

  • irinotecan

  • methotrexate

  • narcotic medicines for pain

  • rifampin

  • rosuvastatin

  • sirolimus

  • topotecan

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • liver disease

  • an unusual or allergic reaction to rolapitant, soybean oil, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Do not take this medicine if you already have nausea and vomiting. Ask your health care provider what to do if you already have nausea.

This medicine should not be used continuously for a long time.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2018 Elsevier